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課程名稱 |
近代腫瘤生物學特論Ⅱ
Modern Tumor Biology Ⅱ |
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開課學期 |
109-2 |
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授課對象 |
醫學院 腫瘤醫學研究所 |
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授課教師 |
歐大諒 |
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課號 |
Onco8014 |
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課程識別碼 |
453 D0150 |
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班次 |
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學分 |
2.0 |
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全/半年 |
半年 |
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必/選修 |
選修 |
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上課時間 |
星期五9,10(16:30~18:20) |
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上課地點 |
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備註 |
本課程中文授課,使用英文教科書。上課地點：基因體5樓會議室。與黃韻如、邵幼雲、沈盈君、曾士傑、蘇聖芳、許家郎合授
總人數上限：20人 |
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Ceiba 課程網頁 |
http://ceiba.ntu.edu.tw/1092Onco8014_ |
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課程簡介影片 |
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核心能力關聯 |
核心能力與課程規劃關聯圖 |
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課程大綱
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為確保您我的權利,請尊重智慧財產權及不得非法影印
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課程概述 |
This course is designed to be an introductory course for those who are interested in understanding oncogenesis. The course will cover several issues including epigenetics, tumor angiogenesis, immunosurveillance, immune escape and inflammation in the process of malignant transformation. Some materials, like cell cycle and chemical carcinogenesis, will not be explained in full detail but will be reviewed briefly. Those who have taken one basic course in tumor biology and graduate students from non-oncology backgrounds are welcome. |
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課程目標 |
Topics to be covered:
1. Tumor suppression genes and oncogene.
2. Transcriptional factors and tumorigenesis.
3. DNA methylation , histone modification and chromatin remodelling in cancer.
4. Angiogenesis in life, tumor and medicine.
5. Immunosurveillance and immune escape of cancer.
6. Inflammation and cancer. |
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課程要求 |
待補 |
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預期每週課後學習時數 |
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Office Hours |
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指定閱讀 |
待補 |
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參考書目 |
John, M., Peter, M. H., Mark, A. I., Joe, W. G., & Craig, B. T.(2008). The Molecular Basis of Cancer. Philadelphia: Saunders Elsevier. |
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評量方式
(僅供參考) |
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週次 |
日期 |
單元主題 |
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第1週 |
2/26 |
32. Molecular Basis of Lung Cancer
20. Cancer Systems Biology
(授課教師:蘇聖芳教授) |
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第2週 |
3/05 |
34. Colon and Rectal Cancer
48. Phase I Trials Today
(授課教師:邵幼雲醫師) |
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第3週 |
3/12 |
52. Cancer immunotherapy with vaccines
and checkpoint blockade
(授課教師:沈盈君醫師) |
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第4週 |
3/19 |
55. RNA as a Therapeutic Molecule
(授課教師:曾士傑教授) |
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第5週 |
3/26 |
Open
(授課教師:歐大諒教授) |
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第6週 |
4/02 |
兒童節遇例假日補假 |
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第7週 |
4/09 |
56. Heat Shock Protein 90 and the
Proteasome ; ER stress and cancer
(授課教師:歐大諒教授) |
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第8週 |
4/16 |
25. High Content Analysis with Cellular
and Tissue Systems Biology: A Bridge
between Cancer Cell Biology and Tissue
Based Diagnostics
(授課教師:許家郎教授) |
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第9週 |
4/23 |
期中考 |
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第10週 |
4/30 |
47. Natural and Acquired Resistance to
Cancer Therapies
(授課教師:蘇聖芳教授) |
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第11週 |
5/07 |
54.Gene therapy and oncolytic viruses;
*including cell therapy
(授課教師:沈盈君) |
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第12週 |
5/14 |
59. Molecular Pathology; virotherapy
(授課教師:曾士傑教授) |
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第13週 |
5/21 |
45. From Bench to Bedside with Targeted
Therapies
50. Monoclonal Antibodies for the Treatment of Cancer
(授課教師:邵幼雲醫師) |
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第14週 |
5/28 |
Discussion
(授課教師:歐大諒教授) |
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第15週 |
6/04 |
4. DNA Repair Pathway
37. Molecular Pathogenesis of Ovarian Cancer
(授課教師:黃韻如教授)
https://meet.google.com/aun-smii-ruv |
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第16週 |
6/11 |
49. Pharmacogenomics
(授課教師:許家郎教授) |
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第17週 |
6/18 |
期末考 |
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